hUC-MSCs therapy for Crohn’s disease: efficacy in TNBS-induced colitis in rats and pilot clinical studyResearch in context

Summary: Background: The use of mesenchymal stem cells (MSCs) has recently emerged as a promising new therapeutic strategy for many diseases including perianal fistulizing Crohn’s disease (CD). Whether hUC-MSCs can promote the healing of luminal ulcer in CD has not been studied so far. Methods: The...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Qinjuan Sun, Shan Li, Ritian Lin, Guangxi Zhao, Jinlai Lu, Bin Liu, Miao Hu, Wei Wang, Xiaoqing Yang, Yushuang Wei, Wenwen Jia, Yanni Hu, Wei Zhang, Jiawen Zhu, Daxiang Cui, Lan Zhong
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2024-05-01
Schriftenreihe:	EBioMedicine
Schlagworte:	Human umbilical cord mesenchymal stem cells Local submucosal injection Intestinal ulceration Crohn’s disease Macrophage Intestinal barrier function
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2352396424001634
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!