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First-in-human e-Flash radiotherapy using a modified conventional C-arm linear accelerator

Background: The FLASH effect is considered being the widening of the therapeutic window at (ultra-)high dose rates due to sparing of normal tissues while preserving tumor response. Our goal was to provide first data on the safety in treating a patient using a conventional linear accelerator converte...

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Principais autores: Jens von der Grün, Riccardo Dal Bello, Serena Psoroulas, Jerome Krayenbuehl, Debra Fesslmeier, Egle Ramelyte, Joanna Mangana, Wendy Smith, Marta Vilalta, Lena Tirpak, Ricky A. Sharma, Matthias Guckenberger, Stephanie Tanadini-Lang, Panagiotis Balermpas
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-01-01
Serier:Clinical and Translational Radiation Oncology
Fag:
Flash-RT
UHDR
Electrons
Malignant melanoma
Clinical translation
Dosimetry
Online adgang:http://www.sciencedirect.com/science/article/pii/S2405630825001399
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