Metabolomic profiling and stable isotope labelling of Trichomonas vaginalis and Tritrichomonas foetus reveal major differences in amino acid metabolism including the production of 2-hydroxyisocaproic acid, cystathionine and S-methylcysteine.

Trichomonas vaginalis and Tritrichomonas foetus are pathogens that parasitise, respectively, human and bovine urogenital tracts causing disease. Using LC-MS, reference metabolomic profiles were obtained for both species and stable isotope labelling with D-[U-13C6] glucose was used to analyse central...

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Principais autores:	Gareth D Westrop, Lijie Wang, Gavin J Blackburn, Tong Zhang, Liang Zheng, David G Watson, Graham H Coombs
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Public Library of Science (PLoS) 2017-01-01
סדרה:	PLoS ONE
גישה מקוונת:	http://europepmc.org/articles/PMC5739422?pdf=render
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