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Evaluation of Safety and Protective Efficacy of a waaJ and spiC Double Deletion Korean Epidemic Strain of Salmonella enterica Serovar Gallinarum

With an aim to develop a highly attenuated and strongly immunogenic distinguishable vaccine candidate, a waaJ (a gene involved in the synthesis of lipopolysaccharide) and spiC (a virulence gene) double deletion Korean epidemic strain of S. enterica ser. Gallinarum (SG005) was constructed. Our result...

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Principais autores: Jun-Feng Zhang, Ke Shang, Bai Wei, Yea-Jin Lee, Jong-Yeol Park, Hyung-Kwan Jang, Se-Yeoun Cha, Min Kang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-11-01
Serier:Frontiers in Veterinary Science
Fag:
DIVA
high attenuation
waaJ
S. enterica ser. Gallinarum
double deletion
spiC
Online adgang:https://www.frontiersin.org/articles/10.3389/fvets.2021.756123/full
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