Deep immune profiling delineates hallmarks of disease heterogeneity in extrapulmonary tuberculosis

Abstract Our understanding of the immune response in tuberculosis (TB) remains incomplete. This applies in particular to extrapulmonary TB (EPTB), a highly heterogeneous disease affecting up to 30% of patients in certain regions. Based on data-driven clustering of blood transcriptomes in an EPTB pat...

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Detalhes bibliográficos

Principais autores:	Sebastian J. Theobald, Kilian Dahm, Dinah Lange, Jannis B. Spintge, Sandra Winter, Angela Klingmüller, Lisa Holsten, Alexander Simonis, Elena De Domenico, Henning Walczak, Martina van Uelft, Joachim L. Schultze, Marc D. Beyer, Thomas Ulas, Isabelle Suárez, Jan Rybniker
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-11-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-025-65561-x
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