Comparison of safety and immunogenicity between high-dose and low-dose quadrivalent influenza vaccines in children aged 6–35 months in China: A randomized, double-blind clinical study

Influenza vaccines for children aged 6–35 months are typically low-dose (0.25 mL, 7.5 μg hemagglutinin per strain). However, studies have shown that high-dose influenza vaccines (0.5 mL, 15 μg hemagglutinin per strain) can enhance protective efficacy without increasing the risk of adverse reactions....

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Autori principali:	Xue Guo, Jingyu Li, Xufeng Dong, Kunpeng Xing, Xiaoteng Xu, Wen Xu, Cangning Wang, Kexin Li, Xuefen Gao, Ye Qiu, Zhanlong Guo, Weijiao Xu, Chenyan Zhao, Yuanjia Ma, Yehong Wu, Xiaoqiang Liu, Guohua Li
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis Group 2026-12-01
Serie:	Human Vaccines & Immunotherapeutics
Soggetti:	Quadrivalent influenza vaccine aged 6–35 months immunogenicity safety clinical trials
Accesso online:	https://www.tandfonline.com/doi/10.1080/21645515.2026.2665017
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