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Sox5 controls the establishment of quiescence in neural stem cells during postnatal development.

Adult stem cell niches relays in the acquisition of a reversible state of quiescence to ensure long-lasting DNA integrity and cell expansion. Neural stem cells (NSCs) in the dentate gyrus (DG) enter quiescence before the adult hippocampal neurogenic niche is fully established. However, the mechanism...

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Autors principals: Cristina Medina-Menéndez, Paula Tirado-Melendro, Lingling Li, Pilar Rodríguez-Martín, Elena Melgarejo-de la Peña, Mario Díaz-García, María Valdés-Bescós, Rafael López-Sansegundo, Aixa V Morales
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2025-07-01
Col·lecció:PLoS Biology
Accés en línia:https://doi.org/10.1371/journal.pbio.3002654
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