Selective pharmacologic targeting of CTPS1 shows single-agent activity and synergizes with BCL2 inhibition in aggressive mantle cell lymphoma

Innovative therapeutic strategies have emerged over the past decade to improve outcomes for most lymphoma patients. Nevertheless, the aggressive presentation seen in high-risk mantle cell lymphoma (MCL) patients remains an unmet medical need. The highly proliferative cells that characterize these t...

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Detalhes bibliográficos

Principais autores:	Romane Durand, Céline Bellanger, Charlotte Kervoëlen, Benoit Tessoulin, Christelle Dousset, Emmanuelle Menoret, Hélène Asnagli, Andrew Parker, Philip Beer, Catherine Pellat-Deceunynck, David Chiron
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Ferrata Storti Foundation 2024-02-01
coleção:	Haematologica
Acesso em linha:	https://haematologica.org/article/view/11464
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