N-nitrosamine Impurities in Medicines: Toxicity, Formation Pathways, Methods of Determination, and Limits (Review)
Introduction. N-nitrosamine compounds are potent genotoxic agents in animal species and some are classified as probable human carcinogens. This group of genotoxic impurities was found in drugs such as angiotensin II receptor blockers, histamine H1 receptor antagonists, and synthetic antidiabetic dru...
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Russo |
| Udgivet: |
LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2020-11-01
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| Serier: | Разработка и регистрация лекарственных средств |
| Fag: | |
| Online adgang: | https://www.pharmjournal.ru/jour/article/view/865 |
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