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SGLT2 inhibitors reduce the salt sensitivity of blood pressure in type 2 diabetes via enhanced postprandial natriuresis

Abstract Background Sodium-glucose cotransporter-2 inhibitors (SGLT2i) lower blood pressure (BP) and provide cardiovascular protection. In animal models, SGLT2i blunt sodium-induced BP elevation, but this effect remains unexplored in humans. We investigated whether SGLT2i reduce the salt sensitivity...

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I tiakina i:
Ngā kaituhi matua: Martina Chiriacò, Domenico Tricò, Luca Sacchetta, Lorenzo Nesti, Noemi Cimbalo, Lorenza Santoni, Simone Gallo, Simona Baldi, Tiziana Scozzaro, Alberto Giannoni, Andrea Natali
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2026-02-01
Rangatū:Cardiovascular Diabetology
Ngā marau:
Blood pressure
Sodium
SGLT2 inhibitors
Salt sensitivity
Urunga tuihono:https://doi.org/10.1186/s12933-026-03095-2
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