Insights Into Mechanisms of Antimicrobial Photodynamic Action Toward Biofilms Using Phenalen-1-One Derivatives as Photosensitizers

IntroductionIn view of increasing resistance against antibiotics and antiseptics, antimicrobial photodynamic therapy (aPDT) may be a promising approach for use in dentistry. The aim of this study was to investigate the mechanism of action of aPDT with the phenalene-1-one derivatives SAPYR and SA-PN-...

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Principais autores:	Denise Muehler, Christina M. Rupp, Sercan Keceli, Christoph Brochhausen, Heiko Siegmund, Tim Maisch, Karl-Anton Hiller, Wolfgang Buchalla, Fabian Cieplik
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2020-10-01
coleção:	Frontiers in Microbiology
Assuntos:	biofilm antimicrobial photodynamic therapy SAPYR chlorhexidine reactive oxygen species phenalen-1-one
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmicb.2020.589364/full
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