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Plasma Metabolomic Profiling Reveals Four Possibly Disrupted Mechanisms in Systemic Sclerosis

Systemic sclerosis (SSc) is a rare systemic autoimmune disorder marked by high morbidity and increased risk of mortality. Our study aimed to analyze metabolomic profiles of plasma from SSc patients by using targeted and untargeted metabolomics approaches. Furthermore, we aimed to detect biochemical...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Thomas Bögl, Franz Mlynek, Markus Himmelsbach, Norbert Sepp, Wolfgang Buchberger, Marija Geroldinger-Simić
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2022-03-01
Schriftenreihe:Biomedicines
Schlagworte:
systemic sclerosis
metabolomics
LC-MS/MS
ion mobility
kynurenine pathway
urea cycle
Online-Zugang:https://www.mdpi.com/2227-9059/10/3/607
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