Relevance of the antibody Fc fragment and epitope valency in protection against malaria sporozoites

Abstract Protection against infection by Plasmodium falciparum sporozoites is mediated in part by antibodies that recognize the repeated (NPNA)3 epitopes of the circumsporozoite protein (CSP). To evaluate the role that the antibody Fc region plays in neutralizing sporozoite infectivity, we assess th...

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Detalhes bibliográficos

Principais autores:	Yevel Flores-Garcia, Manuela C Aguirre-Botero, Prabhanshu Tripathi, Emily Locke, Minah Park, Shamika Mathis-Torres, Berenice Salgado-Jimenez, Sonia Herrera-Arevalo, Anisha Gladston, Beejan Asady, Isabelle Coppens, Rogerio Amino, Fidel Zavala
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer Nature 2026-04-01
Colecção:	EMBO Reports
Acesso em linha:	https://doi.org/10.1038/s44319-026-00788-3
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