Differences in constitutive gene expression of cytochrome P450 enzymes and ATP-binding cassette transporter gene expression between a susceptible and a highly macrocyclic lactone-resistant Haemonchus contortus isolate in the absence of drug-inducible expression

Abstract Background Anthelmintic resistance in ruminants is a widespread problem that has a severe impact on productivity and animal welfare. The helminth Haemonchus contortus is generally considered the most important parasite in small ruminants due to its high pathogenicity and the widespread occu...

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Principais autores:	Natalie Jakobs, Sandro Andreotti, Sabrina Ramünke, Georg von Samson-Himmelstjerna, Jürgen Krücken
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2024-12-01
Series:	Parasites & Vectors
Assuntos:	Haemonchus contortus Anthelmintic resistance Cytochrome P450 P-Glycoproteins ATP-binding cassette transporter Macrocyclic lactones
Acceso en liña:	https://doi.org/10.1186/s13071-024-06568-z
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