Molecular mechanisms of Treg-mediated T cell suppression
CD4+CD25highFoxp3+ regulatory T cells (Tregs) can suppress other immune cells and, thus, are critical mediators of peripheral self-tolerance. On the one hand, Tregs prevent autoimmune disease and allergies. On the other hand, Tregs can avert immune reactions against tumors and pathogens. Despite the...
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| Principais autores: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2012-03-01
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| Serija: | Frontiers in Immunology |
| Teme: | |
| Online dostop: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00051/full |
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