Microenvironment-responsive living hydrogel containing engineered probiotic for treatment of massive bone defects

Self-activating and microenvironment-responsive biomaterials for tissue regeneration would address the escalating need for bone grafting, but remain challenging. The emergence of microbial living therapeutics offers vast potential in regenerative medicine, as genetically engineered probiotics posses...

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Autori principali:	Haoyu Fang, Yanyi Wang, Li Li, Xiaotong Qin, Daoyu Zhu, Pei Liu, Qianhao Yang, Youshui Gao, Zhongmin Shi, Xin Ma, Chao Zhong, Yixuan Chen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	KeAi Communications Co., Ltd. 2025-08-01
Serie:	Bioactive Materials
Soggetti:	Living hydrogel Bacterial engineering Smart biomaterial Sensing-reporting Regenerative medicine
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2452199X25001665
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