Hepatic lipids promote liver metastasis

Obesity predisposes to cancer and a virtual universality of nonalcoholic fatty liver disease (NAFLD). However, the impact of hepatic steatosis on liver metastasis is enigmatic. We find that while control mice were relatively resistant to hepatic metastasis, those which were lipodystrophic or obese,...

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Principais autores:	Yongjia Li, Xinming Su, Nidhi Rohatgi, Yan Zhang, Jonathan R. Brestoff, Kooresh I. Shoghi, Yalin Xu, Clay F. Semenkovich, Charles A. Harris, Lindsay L. Peterson, Katherine N. Weilbaecher, Steven L. Teitelbaum, Wei Zou
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical investigation 2020-09-01
Series:	JCI Insight
Assuntos:	Hepatology Oncology
Acceso en liña:	https://doi.org/10.1172/jci.insight.136215
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