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Identification of Key Pathways Involved in White Strain of Hypsizygus marmoreus Extracts-Induced Cell Death of Human Hepatoma Hep3B Cells by Next Generation Sequencing

White strain of Hypsizygus marmoreus is named as white genius mushroom (WGM) and is a popular food in Taiwan. We have confirmed the cytotoxicity of WGM extracts on human Hep3B liver cancer cells. A total of 8711 significantly differential genes were identified through large-scale transcriptome seque...

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Principais autores: Wei-Sung Li, Kun-Tsung Denzel Lee, Li-Yun Chen, Bang-Jau You, Hong-Zin Lee
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-06-01
coleção:Frontiers in Pharmacology
Assuntos:
white genius mushroom
human Hep3B liver cancer cells
transcriptome
autophagy
mitophagy
reactive oxygen species
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2022.888863/full
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