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Single-Cell Droplet Microfluidic Screening for Antibodies Specifically Binding to Target Cells

Summary: Monoclonal antibodies are a main player in modern drug discovery. Many antibody screening formats exist, each with specific advantages and limitations. Nonetheless, it remains challenging to screen antibodies for the binding of cell-surface receptors (the most important class of all drug ta...

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Autors principals: Nachiket Shembekar, Hongxing Hu, David Eustace, Christoph A. Merten
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018-02-01
Col·lecció:Cell Reports
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2211124718301359
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