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Force and kinetics of fast and slow muscle myosin determined with a synthetic sarcomere–like nanomachine

Abstract Myosin II is the muscle molecular motor that works in two bipolar arrays in each thick filament of the striated (skeletal and cardiac) muscle, converting the chemical energy into steady force and shortening by cyclic ATP–driven interactions with the nearby actin filaments. Different isoform...

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Hauptverfasser: Valentina Buonfiglio, Irene Pertici, Matteo Marcello, Ilaria Morotti, Marco Caremani, Massimo Reconditi, Marco Linari, Duccio Fanelli, Vincenzo Lombardi, Pasquale Bianco
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2024-03-01
Schriftenreihe:Communications Biology
Online-Zugang:https://doi.org/10.1038/s42003-024-06033-8
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