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β-Carboline (FG-7142) modulates fear but not anxiety-like behaviour in zebrafish

Abstract The β-Carboline FG-7142 is a partial inverse agonist at the benzodiazepine allosteric site on the GABA-A receptor that induces anxiogenic, proconvulsant, and appetite-reducing effects in many species, including humans. Seizure-kindling effects have been well studied, however anxiogenic prop...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kale R. Scatterty, Trevor J. Hamilton
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Portfolio 2024-01-01
Cyfres:Scientific Reports
Mynediad Ar-lein:https://doi.org/10.1038/s41598-023-51072-6
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