Fatty acid transporter protein isoform 2 (FATP2) inhibitor lipofermata inhibits Zika virus replication and blocks fatty acid uptake in SH-SY5Y neuroblastoma cell line

ABSTRACT Zika virus (ZIKV) infection in adults is typically mild and self-limiting, but infection during pregnancy can cause fetal and neonatal microcephaly. No approved drugs or vaccines currently exist. ZIKV hijacks host lipid homeostasis to facilitate replication, and inhibitors of fatty acid syn...

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Principais autores:	Songkran Thongon, Chompunuch Boonarkart, Thanyaporn Sirihongthong, Kunlakanya Jitobaom, Kessiri Kongmanas, Prasert Auewarakul
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology 2026-04-01
Serija:	Microbiology Spectrum
Teme:	FATP2 fatty acid uptake lipofermata neuroblastoma virus-lipid interaction Zika
Online dostop:	https://journals.asm.org/doi/10.1128/spectrum.02140-25
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