The value of increasing sequencing depth for noninvasive prenatal screening for whole chromosomal aneuploidy

Abstract To evaluate the value of increasing sequencing depths of non-invasive prenatal testing (NIPT) for fetal chromosomal aneuploidies based on the semiconductor sequencing platform. This study recruited a cohort of 59,800 singleton pregnancies from Guangdong Women and Children Hospital between J...

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Detalhes bibliográficos

Principais autores:	Dongmei Wang, Fangfang Guo, Yaping Hou, Haishan Peng, Tingting Hu, Jiexia Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-01-01
coleção:	Scientific Reports
Assuntos:	Non-invasive prenatal testing (NIPT) Sequencing depth Fetal chromosome aneuploidy Positive predictive value
Acesso em linha:	https://doi.org/10.1038/s41598-025-87218-x
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