Integrated Genetic and Protein Mechanisms Underlying Glucagon-like Peptide-1 Receptor Agonists in Treating Diabetes Mellitus and Weight Loss

Glucagon-like peptide-1 receptor (GLP1R) agonists, such as semaglutide, are used for treating type 2 diabetes mellitus and promoting weight loss. This study investigates genetic and molecular mechanisms underlying GLP1R activation using a novel in silico approach to identify effects on metabolism, g...

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Principais autores:	Lucas Francis, Merlin G. Butler
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-11-01
Colecção:	Current Issues in Molecular Biology
Assuntos:	glucagon-like peptide-1 (GLP1) receptor (GLP1R) gene GLP1R agonist gene-gene or protein interactions, biological processes, functions, pathways and associated diseases obesity weight loss insulin
Acesso em linha:	https://www.mdpi.com/1467-3045/47/12/1007
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