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Prognostic signature and therapeutic drug identification for dilated cardiomyopathy based on necroptosis via bioinformatics and experimental validation

Abstract Necroptosis, a type of programmed cell death, has been increasingly linked to cardiovascular disease development, yet its role in dilated cardiomyopathy (DCM) remains unclear. In this study, we analyzed the GSE5406 dataset from the GEO database to explore necroptosis-related prognostic sign...

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Principais autores: Han Yang, Zhenwei Wang, Yawei Xu, Yimei Du, Haibo Yang, Yang Lu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-01-01
Serier:Scientific Reports
Fag:
Necroptosis
Dilated cardiomyopathy
Fenofibrate
Necroptosis-related genes
Prognostic assessment
Online adgang:https://doi.org/10.1038/s41598-024-83455-8
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