Spermatid-specific linker histone HILS1 is a poor condenser of DNA and chromatin and preferentially associates with LINE-1 elements

Abstract Background Linker histones establish and maintain higher-order chromatin structure. Eleven linker histone subtypes have been reported in mammals. HILS1 is a spermatid-specific linker histone, and its expression overlaps with the histone–protamine exchange process during mammalian spermiogen...

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Autori principali:	Laxmi Narayan Mishra, Vasantha Shalini, Nikhil Gupta, Krittika Ghosh, Neeraj Suthar, Utsa Bhaduri, M. R. Satyanarayana Rao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2018-08-01
Serie:	Epigenetics & Chromatin
Soggetti:	Spermiogenesis Chromatin remodeling Linker histone Circular dichroism ChIP sequencing
Accesso online:	http://link.springer.com/article/10.1186/s13072-018-0214-0
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