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Standardisation of basal medium for reproducible culture of human annulus fibrosus and nucleus pulposus cells

Abstract Background The lifetime prevalence of degenerative disc disease is dramatically high. Numerous investigations on disc degeneration have been performed on cells from annulus fibrosus (AF) and nucleus pulposus (NP) of the intervertebral disc (IVD) in cell culture experiments utilising a broad...

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Principais autores: Ann-Kathrin Schubert, Jeske J. Smink, Matthias Pumberger, Michael Putzier, Michael Sittinger, Jochen Ringe
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2018-08-01
Serier:Journal of Orthopaedic Surgery and Research
Fag:
Annulus fibrosus
Nucleus pulposus
Basal medium
Cell growth
Dedifferentiation
Disc marker
Online adgang:http://link.springer.com/article/10.1186/s13018-018-0914-y
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