A SNARE protective pool antagonizes APOL1 renal toxicity in Drosophila nephrocytes
Abstract Background People of Sub-Saharan African ancestry are at higher risk of developing chronic kidney disease (CKD), attributed to the Apolipoprotein L1 (APOL1) gene risk alleles (RA) G1 and G2. The underlying mechanisms by which the APOL1-RA precipitate CKD remain elusive, hindering the develo...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BMC
2023-11-01
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| Series: | Cell & Bioscience |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1186/s13578-023-01147-8 |
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