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Identification and Pharmacokinetic Studies on Complanatuside and Its Major Metabolites in Rats by UHPLC-Q-TOF-MS/MS and LC-MS/MS

The metabolic and pharmacokinetic studies on complanatuside, a quality marker of a Chinese materia medicatonic, Semen Astragali Complanati, were carried out. The UHPLC-Q-TOF/MS (ultra-high performance liquid chromatography coupled with electrospray ionization tandem quadrupole-time-of-flight mass sp...

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Principais autores: Yu-Feng Yao, Chao-Zhan Lin, Fang-Le Liu, Run-Jing Zhang, Qiu-Yu Zhang, Tao Huang, Yuan-Sheng Zou, Mei-Qi Wang, Chen-Chen Zhu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2018-12-01
Serier:Molecules
Fag:
complanatuside
metabolism
pharmacokinetics
UHPLC-Q-TOF-MS
HPLC-MS/MS
Online adgang:http://www.mdpi.com/1420-3049/24/1/71
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