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Differential expression of HIV target cells CCR5 and α4β7 in tissue resident memory CD4 T cells in endocervix during the menstrual cycle of HIV seronegative women

BackgroundOvarian hormones are known to modulate the immune system in the female genital tract (FGT). We sought to define the impact of the menstrual cycle on the mucosal HIV target cell levels, and tissue-resident CD4 T cells.Materials and methodsHere, we characterized the distribution, phenotype,...

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Principais autores: Sakthivel Govindaraj, Staple Tyree, Gina Bailey Herring, Sadia J. Rahman, Hemalatha Babu, Chris Ibegbu, Marisa R. Young, C. Christina Mehta, Lisa B. Haddad, Alicia K. Smith, Vijayakumar Velu
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2024-09-01
סדרה:Frontiers in Immunology
נושאים:
HIV target cells
HIV susceptibility
TRM
menstrual cycle phase
endocervix
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1456652/full
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