Oral-nasopharyngeal dendritic cells mediate T cell-independent IgA class switching on B-1 B cells.

Native cholera toxin (nCT) as a nasal adjuvant was shown to elicit increased levels of T-independent S-IgA antibody (Ab) responses through IL-5- IL-5 receptor interactions between CD4+ T cells and IgA+ B-1 B cells in murine submandibular glands (SMGs) and nasal passages (NPs). Here, we further inves...

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Autors principals:	Kosuke Kataoka, Keiko Fujihashi, Yutaka Terao, Rebekah S Gilbert, Shinichi Sekine, Ryoki Kobayashi, Yoshiko Fukuyama, Shigetada Kawabata, Kohtaro Fujihashi
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2011-01-01
Col·lecció:	PLoS ONE
Accés en línia:	http://europepmc.org/articles/PMC3183055?pdf=render
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