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An update on the characterization of immunoglobulin loci in Ambystoma mexicanum

BackgroundWe previously reported the genomic characterization of immunoglobulin loci in Ambystoma mexicanum of the laboratory d/d white strain, where the IGH locus gene orientation was incompatible with VDJ recombination, suggesting scaffold orientation errors. A novel 29.1 Gbp A. mexicanum genome d...

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Enregistré dans:
Auteurs principaux: Stephanie Saint Remy-Hernández, Diana Laura Pacheco-Olvera, Elizabeth Ernestina Godoy-Lozano, Juan Miguel-Ruiz, Juan Téllez-Sosa, Humberto Valdovinos-Torres, Nancy Rivas, Constantino López-Macías, Jesús Martínez-Barnetche
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2026-02-01
Collection:Frontiers in Immunology
Sujets:
Ambystoma
comparative genomics
copy number variation
Ig loci
immunoglobulin genes
Accès en ligne:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1736245/full
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