Dual CARM1-and IKZF3-targeting: A novel approach to multiple myeloma therapy synergy between CARM1 inhibition and IMiDs

Advancements in the treatment of multiple myeloma (MM) have resulted in an improvement in the survival rate. However, there continues to be an urgent need for improved therapies. The protein arginine methyltransferase, CARM1 (coactivator associated arginine methyltransferase 1), is emerging as a pot...

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Prif Awduron:	Wei Ni, Swati Garg, Basudev Chowdhury, Martin Sattler, Dana Sanchez, Chengcheng Meng, Taisei Akatsu, Katherine A. Donovan, Jun Qi, Michelle Y. Wang, Cara Ann Starnbach, Xiaoxi Liu, Maria Tarazona Guzman, Wei Pin Teh, Richard Stone, James D. Griffin, Sara Buhrlage, Ellen Weisberg
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2025-03-01
Cyfres:	Molecular Therapy: Oncology
Pynciau:	MT: Regular Issue multiple myeloma MM immunomodulatory drugs IMiDs CARM1
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S2950329925000219
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!