Small Extracellular Vesicles Derived from NF2-Associated Schwannoma Cells Modulate Tumor Progression and Immunity via HSP90

In-depth exploration of tumor immune suppression mechanisms may provide new therapeutic options for NF2-associated tumors. In this study, we found that sEVs secreted by NF2-associated schwannomas (NF2-EVs) facilitate the conversion of CD14⁺ monocytes into an MDSC-like phenotype, showcasin...

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Detalhes bibliográficos

Principais autores:	Ying Wang, Yuan Ren, Qi Zhang, Chao Zhang, Minjun Yan, Xin Ma, Bo Wang, Peng Li, Pinan Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-10-01
coleção:	Current Oncology
Assuntos:	NF2-related schwannomatosis (NF2-SWN) exosome MDSC HSP90 AKT
Acesso em linha:	https://www.mdpi.com/1718-7729/32/10/569
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