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Catalytic enantioselective synthesis of inherently chiral calix[4]arenes via organocatalyzed aromatic amination enabled desymmetrization

Abstract Inherently chiral calix[4]arenes represent a distinct class of chiral frameworks whose chirality arises from the dissymmetry of the entire molecule. Although these chiral scaffolds have been widely applied in various research fields, their catalytic enantioselective synthesis remains largel...

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Detalhes bibliográficos
Principais autores: Mengyao Yuan, Wansen Xie, Shaoze Yu, Tong Liu, Xiaoyu Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2025-04-01
Colecção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-025-59221-3
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