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Molecular cloning, expression analysis and functional characterization of chicken cytochrome P450 27A1: A novel mitochondrial vitamin D3 25-hydroxylase

ABSTRACT: Vitamin D3 is hydroxylated by cytochrome P450 (CYP) before exerting biological effects. The chicken CYP involved in vitamin D3 25-hydroxylation has yet to be cloned, and little is known about its functional characteristics, tissue distribution, and cellular expression. We identified a nove...

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Principais autores: S. Shang, Z. He, W. Hou, X. Chen, X. Zhao, H. Han, S. Chen, S. Yang, F. Tai
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2023-08-01
coleção:Poultry Science
Assuntos:
chicken
cytochrome P450 27A1
metabolism
vitamin D3
mitochondria
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0032579123002663
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