Predictors of caspofungin exposure-response relationship: a retrospective cohort study on therapeutic drug monitoring parameters

IntroductionThis study aimed to characterize the exposure-response relationship of caspofungin through analysis of trough serum concentration (Cmin) associated with clinical efficacy, while identifying clinically determinants of Cmin.MethodsA single-center retrospective cohort study collected therap...

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Principais autores:	Mingwei Meng, Ruhua Wei, Yating Lu, Wen Cao, Kai Mo, Zheng Huang, Yane Qin, Xiaobu Lan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-07-01
coleção:	Frontiers in Pharmacology
Assuntos:	caspofungin trough concentration antifungal efficacy therapeutic drug monitoring
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1620179/full
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