Activation of mTOR mediates hyperglycemia-induced renal glomerular endothelial hyperpermeability via the RhoA/ROCK/pMLC signaling pathway

Abstract Objective Hyperglycemia is associated with albuminuria and renal glomerular endothelial dysfunction in patients with diabetic nephropathy. The mTOR and RhoA/ROCK signaling pathways are involved in glomerular filtration barrier (GFB) regulation, but their role in high glucose (HG)-induced GF...

Deskribapen osoa

Xehetasun bibliografikoak

Egile Nagusiak:	Xiaolin Chen, Jianhui Chen, Xianfan Li, Zengpu Yu
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2021-10-01
Saila:	Diabetology & Metabolic Syndrome
Gaiak:	Glomerular endothelial cell Permeability Myosin light chain High glucose RhoA/ROCK
Sarrera elektronikoa:	https://doi.org/10.1186/s13098-021-00723-7
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!