Dual adaptive strategies in Candida glabrata under tunicamycin stress: petite mutations and chromosome C aneuploidy drive transient drug resistance
BackgroundCandida glabrata is an opportunistic fungal pathogen known for its ability to rapidly develop resistance to antifungal agents. Tunicamycin (TUN), an inhibitor of N-linked glycosylation, induces Endoplasmic Reticulum (ER) stress, but the adaptive mechanisms enabling C. glabrata to survive T...
Salvato in:
| Autori principali: | , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2025-10-01
|
| Serie: | Frontiers in Microbiology |
| Soggetti: | |
| Accesso online: | https://www.frontiersin.org/articles/10.3389/fmicb.2025.1675175/full |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|