Metabolically Engineered Extracellular Vesicles Released From a Composite Hydrogel Delivery System Regulate the Microenvironment for Periprosthetic Osteolysis Treatment

ABSTRACT Despite remarkable progress in total joint arthroplasty, aseptic loosening of titanium (Ti) alloy persists as a critical clinical challenge due to the poor wear resistance and biological inertness of such implants. Targeting of inflammatory osteolysis and remodelling of the osseointegration...

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Váldodahkkit:	Chenchen Wang, Jiang Ju, Chao Fu, Bingbo Bao, Tianhui Ren, Yanan Li, Yuan Wang, Sheng Han, Xuan Huang, Hongxing Hu, Xianyou Zheng
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Wiley 2025-06-01
Ráidu:	Journal of Extracellular Vesicles
Fáttát:	extracellular vesicles hydrogel macrophage periprosthetic osteolysis titanium alloys
Liŋkkat:	https://doi.org/10.1002/jev2.70098
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