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Contribution of DEAF1 structural domains to the interaction with the breast cancer oncogene LMO4.

The proteins LMO4 and DEAF1 contribute to the proliferation of mammary epithelial cells. During breast cancer LMO4 is upregulated, affecting its interaction with other protein partners. This may set cells on a path to tumour formation. LMO4 and DEAF1 interact, but it is unknown how they cooperate to...

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Bibliografiske detaljer
Principais autores: Liza Cubeddu, Soumya Joseph, Derek J Richard, Jacqueline M Matthews
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2012-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3378519?pdf=render
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