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The fibrin-derived peptide FX06 protects human pulmonary endothelial cells against the COVID-19-triggered cytokine storm

IntroductionCoronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been a major health emergency since its emergence in late 2019. Endothelial dysfunction is a hallmark of COVID-19, leading to severe illness, i.e. coagulopathy, multi-organ fa...

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Principais autores: Zhiran Wang, Dmitrii Lebedev, Simeng Li, Sudharshan Rao, Kevin Wu, Lorcan Doyle, Kieran Wynne, Alfonso Blanco, Margaritha M. Mysior, Jeremy C. Simpson, Dimitri Scholz, Petra Wülfroth, Kai Zacharowski, Walter Kolch, Vadim Zhernovkov, Günther Eissner
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-06-01
coleção:Frontiers in Immunology
Assuntos:
endothelial dysfunction
COVID-19
cytokine
FX06
vascular leakage
ARDS
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1591860/full
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