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Cytolethal distending toxin from Glaesserella parasuis induces ferroptosis in porcine alveolar macrophages and mice

Abstract Glaesserella parasuis cytolethal distending toxin (GpCDT) is a bacterial genotoxin whose main action is to activate DNA damage responses, induce cell cycle arrest, and induce the apoptosis of host cells. In our previous studies, we reported that cells incubated with GpCDT exhibited changes...

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Bibliografiske detaljer
Principais autores: Shiyu Xu, Li Lei, Zhen Yang, Yu Wang, Senyan Du, Qin Zhao, Xiaobo Huang, Sanjie Cao, Rui Wu, Yiping Wang, Qigui Yan, Yiping Wen
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-04-01
Serier:Veterinary Research
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Online adgang:https://doi.org/10.1186/s13567-025-01520-0
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