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Triptolide alleviates cerebral ischemia/reperfusion injury via regulating the Fractalkine/CX3CR1 signaling pathway

Purpose: To evaluate the potential efficacy of Triptolide (TP) on cerebral ischemia/reperfusion injury (CIRI) and to uncover the underlying mechanism through which TP regulates CIRI. Methods: We constructed a middle cerebral artery occlusion/reperfusion (MCAO/R) mouse model to simulate CIRI, and est...

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Principais autores: Jiajun Zhou, Wei Ye, Ling Chen, Junheng Li, Yijun Zhou, Chunfeng Bai, Lian Luo
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-06-01
Serier:Brain Research Bulletin
Fag:
Cerebral ischemia/reperfusion injury
Triptolide
CTSS
Fractalkine
CX3CR1
Online adgang:http://www.sciencedirect.com/science/article/pii/S0361923024000728
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