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New composite phenotypes enhance chronic kidney disease classification and genetic associations.

Chronic kidney disease (CKD) is a multifactorial condition driven by diverse etiologies that lead to a gradual loss of kidney function. Although genome-wide association studies (GWAS) have identified numerous genetic loci linked to CKD, a large portion of its genetic basis remains unexplained. This...

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Huvudupphov: Kim Ngan Tran, Heidi G Sutherland, Andrew J Mallett, Lyn R Griffiths, Rodney A Lea
Materialtyp: Artigo
Språk:Inglês
Utgiven: Public Library of Science (PLoS) 2025-05-01
Serie:PLoS Genetics
Länkar:https://doi.org/10.1371/journal.pgen.1011718
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