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DNA damage induced during mitosis undergoes DNA repair synthesis.

Understanding the mitotic DNA damage response (DDR) is critical to our comprehension of cancer, premature aging and developmental disorders which are marked by DNA repair deficiencies. In this study we use a micro-focused laser to induce DNA damage in selected mitotic chromosomes to study the subseq...

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Bibliografiske detaljer
Principais autores: Veronica Gomez Godinez, Sami Kabbara, Adria Sherman, Tao Wu, Shirli Cohen, Xiangduo Kong, Jose Luis Maravillas-Montero, Zhixia Shi, Daryl Preece, Kyoko Yokomori, Michael W Berns
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2020-01-01
Serier:PLoS ONE
Online adgang:https://doi.org/10.1371/journal.pone.0227849
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