AKR1B1 drives hyperglycemia-induced metabolic reprogramming in MASLD-associated hepatocellular carcinoma

Background & Aims: The mechanism behind the progressive pathological alteration in metabolic dysfunction-associated steatotic liver disease/steatohepatitis (MASLD/MASH)-associated hepatocellular carcinoma (HCC) is poorly understood. In the present study, we investigated the role of the polyol pa...

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Autors principals:	NP Syamprasad, Siddhi Jain, Bishal Rajdev, Samir Ranjan Panda, Gangasani Jagadeesh Kumar, Khaja Moinuddin Shaik, P.A. Shantanu, Veerabhadra Swamy Challa, Sachin B. Jorvekar, Roshan M. Borkar, Jayathirtha Rao Vaidya, Dinesh Mani Tripathi, V.G.M. Naidu
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2024-02-01
Col·lecció:	JHEP Reports
Matèries:	MASLD/MASH HCC Metabolism Warburg effect NARI-29 epalrestat
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2589555923003051
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