Erythrocyte adenosine A2B receptor prevents cognitive and auditory dysfunction by promoting hypoxic and metabolic reprogramming.

Hypoxia drives aging and promotes age-related cognition and hearing functional decline. Despite the role of erythrocytes in oxygen (O2) transport, their role in the onset of aging and age-related cognitive decline and hearing loss (HL) remains undetermined. Recent studies revealed that signaling thr...

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Detalhes bibliográficos

Principais autores:	Qingfen Qiang, Jeanne M Manalo, Hong Sun, Yujin Zhang, Anren Song, Alexander Q Wen, Y Edward Wen, Changhan Chen, Hong Liu, Ying Cui, Travis Nemkov, Julie A Reisz, George Edwards Iii, Fred A Perreira, Rodney E Kellems, Claudio Soto, Angelo D'Alessandro, Yang Xia
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2021-06-01
coleção:	PLoS Biology
Acesso em linha:	https://doi.org/10.1371/journal.pbio.3001239
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