Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B12 delivery and repair
Abstract G-proteins function as molecular switches to power cofactor translocation and confer fidelity in metal trafficking. The G-protein, MMAA, together with MMAB, an adenosyltransferase, orchestrate cofactor delivery and repair of B12-dependent human methylmalonyl-CoA mutase (MMUT). The mechanism...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Portfolio
2023-07-01
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| Seria: | Nature Communications |
| Dostęp online: | https://doi.org/10.1038/s41467-023-40077-4 |
| Etykiety: |
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