20S proteasome and glyoxalase 1 activities decrease in erythrocytes derived from Alzheimer’s disease patients

As a result of accumulating methylglyoxal and advanced glycation end products in the brains of patients with Alzheimer’s disease, it is considered a protein precipitation disease. The ubiquitin proteasome system is one of the most important mechanisms for cells to degrade proteins, and thus is very...

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Autori principali:	Hui Lv, Gui-Yuan Wei, Can-Shou Guo, Yu-Feng Deng, Yong-Ming Jiang, Ce Gao, Chong-Dong Jian
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wolters Kluwer Medknow Publications 2020-01-01
Serie:	Neural Regeneration Research
Soggetti:	20S proteasomal activity; Alzheimer’s disease; erythrocytes; glyoxalase 1; H2O2; malondialdehyde; nerve regeneration; total ubiquitin
Accesso online:	http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=1;spage=178;epage=183;aulast=Lv
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